From the album, Mule Variations. Written by Tom Waits and Kathleen Brennan. That’s Charlie Musselwhite playing the blues harp.
This whole lyric is hilarious but these 4 lines get me very time:
“When the weather gets rough and it’s whiskey in the shade
It’s best to wrap your savior up in cellophane
He flows like the big muddy but that’s okay
Pour him over ice cream for a nice parfait”